QC Ware calculates enzyme energy with hybrid quantum-classical method
This hybrid method accelerates molecular simulations for industrially relevant enzymes, bridging the gap between quantum hardware and real-world scientific problems while proving scalability for larger systems.

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QC Ware reports demonstrating a hybrid quantum-classical workflow by combining its Promethium software with IBM’s 156-qubit Heron superconducting quantum processor. The demonstration calculated electrostatic interaction energy for nitric oxide reductase, a chemically complex metalloenzyme system relevant to drug discovery, catalysis, and materials science. “This demonstration shows how classical and quantum computing can be combined to address meaningful computational chemistry problems,” said Dr. Kin-Joe Sham, Co-Founder and COO at QC Ware. This work highlights how Promethium can integrate with quantum hardware for scientifically relevant calculations. Promethium and IBM Quantum Calculate Nitric Oxide Reductase Energy IBM’s 156-qubit Heron superconducting quantum processor recently powered a workflow that calculated the electrostatic interaction energy of a complex biological molecule, marking a step toward utilizing increasingly powerful quantum hardware for practical scientific challenges. This work demonstrates a targeted application of combined computing, rather than a general proof-of-concept, and builds upon QC Ware’s prior research in the field. Researchers leveraged Promethium’s GPU-native architecture, which enables calculations on larger molecular systems and a greater number of compounds than previously possible, achieving speed increases of up to 20 times compared to conventional platforms for select workloads. This accelerated processing allows scientists to generate molecular-level insights in hours instead of weeks, significantly speeding up decision-making processes in several key scientific areas.
The team’s focus on nitric oxide reductase highlights their commitment to tackling challenging molecular systems relevant to real-world applications. According to QC Ware, Promethium not only delivers high-performance computational chemistry but also provides a foundation for exploring future hybrid workflows that integrate quantum computing more deeply into scientific research. This technology demonstration is not yet a fully integrated Promethium product capability, but represents a significant advancement in the field. This demonstration shows how classical and quantum computing can be combined to address meaningful computational chemistry problems. Dr. Kin-Joe Sham, Co-Founder and COO at QC Ware Source: https://www.prnewswire.com/news-releases/qc-ware-demonstration-of-hybrid-quantum-classical-workflow-using-promethium-and-ibm-quantum-302844876.html Stay currentSee today’s quantum computing news on Quantum Zeitgeist for the latest breakthroughs in qubits, hardware, algorithms, and industry deals. Tags: The Quant The Quant possesses over two decades of experience in start-up ventures and financial arenas, brings a unique and insightful perspective to the quantum computing sector. This extensive background combines the agility and innovation typical of start-up environments with the rigor and analytical depth required in finance. Such a blend of skills is particularly valuable in understanding and navigating the complex, rapidly evolving landscape of quantum computing and quantum technology marketplaces. The quantum technology marketplace is burgeoning, with immense growth potential. This expansion is not just limited to the technology itself but extends to a wide array of applications in different industries, including finance, healthcare, logistics, and more. Latest Posts by The Quant: IonQ’s quantum space division wins $25.6M radar imagery contract August 7, 2026 SpaceX poised to hit $10 trillion, stacking five businesses August 6, 2026 Researchers map quantum dynamics to free probability theory August 6, 2026
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