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Python in the front, party in the Backline: compiling quantum workloads across CPUs, GPUs, and FPGAs

Joseph K. L. Lee, Mehrdad Malekmohammadi, Hong-Sheng Zheng, Shuli Shu, Cheick Doumbia, Kalman Szenes, Mehran Zamani Abnili, Thomas Ainsworth, Matthew Seymour, Thomas Germain, Leonhard Neuhaus, Josh Izaac, Lee J. O'Riordan
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We demonstrate the compilation and execution of several quantum Quantum Physics arXiv:2609.09270 (quant-ph) [Submitted on 8 Sep 2026] Title:Python in the front, party in the Backline: compiling quantum workloads across CPUs, GPUs, and FPGAs Authors:Joseph K. CPUs, GPUs, and other accelerators introduce a different challenge: as infrastructure becomes increasingly heterogeneous, programming across different devices and their associated abstractions becomes more complex. We demonstrate the compilation and execution of several quantum workloads with low-latency data movement across a mix of CPUs, GPUs, and FPGAs, for both local and distributed remote hardware targets, all from a vendor-agnostic Python frontend.
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Quantum Physics arXiv:2609.09270 (quant-ph) [Submitted on 8 Sep 2026] Title:Python in the front, party in the Backline: compiling quantum workloads across CPUs, GPUs, and FPGAs Authors:Joseph K. L. Lee, Mehrdad Malekmohammadi, Hong-Sheng Zheng, Shuli Shu, Cheick Doumbia, Kalman Szenes, Mehran Zamani Abnili, Thomas Ainsworth, Matthew Seymour, Thomas Germain, Leonhard Neuhaus, Josh Izaac, Lee J. O'Riordan View a PDF of the paper titled Python in the front, party in the Backline: compiling quantum workloads across CPUs, GPUs, and FPGAs, by Joseph K. L. Lee and 12 other authors View PDF HTML (experimental) Abstract:Moving from quantum research and development to production-grade, fault-tolerant quantum workload execution remains one of the most significant challenges facing quantum platform builders. While Python frameworks have enabled an easy entry point for quantum algorithm design, the low-latency requirements for real-time quantum error correction (QEC) demand performance that traditional interpreted environments cannot provide. FPGAs and ASICs play a central role at these layers, but their specialized programming models make development rigid and time-consuming. CPUs, GPUs, and other accelerators introduce a different challenge: as infrastructure becomes increasingly heterogeneous, programming across different devices and their associated abstractions becomes more complex. Allowing researchers to write workloads in high-level languages that map to low-latency execution across diverse distributed target platforms will enable the development of key infrastructure for utility-scale quantum systems. For this, we introduce $\textit{Backline}$, a heterogeneous compilation and runtime framework built within PennyLane and Catalyst. Backline allows us to design and build quantum-classical workloads for high-performance and low-latency devices, with compilation directly from a Python interface through MLIR. We demonstrate the compilation and execution of several quantum workloads with low-latency data movement across a mix of CPUs, GPUs, and FPGAs, for both local and distributed remote hardware targets, all from a vendor-agnostic Python frontend. With an AMD VPK120 FPGA board as the controller, issuing each round from its hardware-handshake engine, we measured median steady-state round-trip latencies over RoCE v2 of $2.305~\mu$s to an AMD Ryzen Threadripper PRO CPU and $4.5~\mu$s to an AMD Instinct MI210 GPU across $10^6-1$ rounds per path, demonstrating microsecond-scale synchronous co-processing. Subjects: Quantum Physics (quant-ph); Distributed, Parallel, and Cluster Computing (cs.DC); Programming Languages (cs.PL) Cite as: arXiv:2609.09270 [quant-ph] (or arXiv:2609.09270v1 [quant-ph] for this version) https://doi.org/10.48550/arXiv.2609.09270 Focus to learn more arXiv-issued DOI via DataCite (pending registration) Submission history From: Lee James O'Riordan [view email] [v1] Tue, 8 Sep 2026 18:00:00 UTC (544 KB) Full-text links: Access Paper: View a PDF of the paper titled Python in the front, party in the Backline: compiling quantum workloads across CPUs, GPUs, and FPGAs, by Joseph K. L. Lee and 12 other authorsView PDFHTML (experimental)TeX Source view license Current browse context: quant-ph new | recent | 2026-09 Change to browse by: cs cs.DC cs.PL References & Citations INSPIRE HEP NASA ADSGoogle Scholar Semantic Scholar export BibTeX citation Loading... BibTeX formatted citation × loading... 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quantum-programming
quantum-algorithms
quantum-error-correction
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