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This $64 Million Biotech Exit Seemingly Missed a 77% One-Day Surge on Gilead Takeover Deal

newsfeedback@fool.com (Jonathan Ponciano)
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⚡ Quantum Brief
Cormorant Asset Management fully exited its $64 million Arcellx stake in Q4 2025, selling 775,000 shares—4.4% of its prior AUM—just weeks before the stock surged 77% on Gilead’s $7.8 billion takeover bid. The sale occurred in February 2026, per SEC filings, valuing the transaction at $63.63 million based on prior quarter-end prices, eliminating the fund’s entire position in the biotech firm. Arcellx shares now trade at $114.51, up 60% year-over-year, driven by its CAR-T therapy for multiple myeloma, which prompted Gilead’s acquisition offer of $115 per share plus milestone payments. Gilead’s deal, announced post-exit, builds on a 2022 partnership, accelerating Arcellx’s pipeline targeting blood cancers and solid tumors despite its $228.9 million annual net loss. The missed surge highlights timing risks in biotech investing, though Arcellx’s $6.7 billion valuation reflects strong industry demand for its cell therapy platforms.
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By Jonathan Ponciano – Mar 16, 2026 at 7:13PM ESTKey PointsCormorant Asset Management sold 775,000 Arcellx shares in the fourth quarter.The fund’s quarter-end position value in Arcellx decreased by $63.63 million, reflecting a complete position sale during the period.The position previously accounted for 4.4% of the fund’s AUM in the prior quarter, making this a notable exit.On February 17, 2026, Cormorant Asset Management disclosed in a regulatory filing that it sold its entire stake in Arcellx (ACLX +0.10%), an estimated $63.63 million transaction based on last-disclosed position values.What happenedAccording to an SEC filing dated February 17, 2026, Cormorant Asset Management sold 775,000 shares of Arcellx, fully liquidating its position. The quarter-end value of the fund’s Arcellx stake declined by $63.63 million as a result of the exit.What else to knowThe fund’s sale of Arcellx reduced its position from 4.4% of 13F reportable AUM in the previous quarter to zero.Top holdings after the filing:NASDAQ:PRAX: $280.00 million (15.9% of AUM)NASDAQ:BBOT: $223.84 million (12.7% of AUM)NASDAQ:ABVX: $182.05 million (10.3% of AUM)NASDAQ:EYPT: $151.00 million (8.6% of AUM)NASDAQ:RAPP: $91.85 million (5.2% of AUM)As of Monday, Arcellx shares were priced at $114.51, up a staggering 60% over the past year and well outperforming the S&P 500’s roughly 19% gain in the same period.Company overviewMetricValuePrice (as of Monday)$114.51Market capitalization$6.7 billionRevenue (TTM)$22.3 millionNet income (TTM)($228.9 million)Company snapshotArcellx develops immunotherapies targeting cancer and incurable diseases, with lead candidates including CART-ddBCMA for multiple myeloma and pipeline assets for AML, MDS, and solid tumors.The company operates as a clinical-stage biotechnology company focused on research and development of cell-based therapies.It serves healthcare providers and research institutions seeking advanced oncology and hematology treatments for relapsed or refractory patient populations.Arcellx is advancing proprietary ddCAR and ARC-T cell platforms to address high unmet medical needs in relapsed or refractory cancers. The company’s pipeline includes multiple candidates targeting both hematologic malignancies and solid tumors.What this transaction means for investorsArcellx shares are up 80% this year, and there’s one clear catalyst for that move. The company has been developing next-generation CAR-T cell therapies designed to treat cancers such as multiple myeloma. Its lead therapy, anitocabtagene autoleucel, has shown strong clinical responses and attracted the attention of larger pharmaceutical companies eager to expand their oncology pipelines.That interest ultimately culminated in a takeover agreement from Gilead Sciences last month, valuing Arcellx at about $7.8 billion and offering shareholders $115 per share in cash plus a potential additional payment tied to future sales milestones. The deal builds on an existing 2022 collaboration between the two companies around the therapy and could accelerate development and commercialization if regulatory approvals move forward.Still, it’s important to note this pop happened after Cormorant’s reported exit, a reminder that even smart investments can miss out due to timing flukes. What ultimately matters more is identifying companies building therapies that larger industry players ultimately want to own.About the AuthorJonathan Ponciano is a contributing stock market analyst at The Motley Fool. He has nearly a decade of experience as a financial journalist, most recently as an editor and senior reporter at Forbes focused on markets, technology, and entrepreneurship. Jonathan has also written for Investopedia and the Los Angeles Business Journal. He holds a dual B.A. in Business Journalism and Economics from the University of North Carolina at Chapel Hill and an M.B.A. from Columbia Business School. A North Carolina native now based in New York City, Jonathan has also lived in Mexico City and Los Angeles.CMFjonponcStocks MentionedArcellxNASDAQ: ACLX$114.51(+0.10%)+$0.12*Average returns of all recommendations since inception. Cost basis and return based on previous market day close.

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