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Esperion Therapeutics (ESPR) Misses Q4 Earnings Estimates

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Esperion Therapeutics reported Q4 2025 earnings of $0.22 per share, missing the Zacks Consensus Estimate of $0.23 by -5.38%, despite a year-over-year improvement from a $0.1 loss. Revenue reached $168.45 million, exceeding estimates by 4.90% and more than doubling the $69.11 million reported in Q4 2024, marking four consecutive quarters of revenue beats. The stock has declined 17.8% year-to-date, underperforming the S&P 500’s 0.7% drop, with future movement hinging on management’s earnings call guidance and industry trends. Earnings outlook remains mixed, with a Zacks Rank #3 (Hold) and consensus estimates of -$0.04 EPS next quarter and $0.18 for the fiscal year, reflecting cautious analyst sentiment. Peer Nektar Therapeutics, also in biopharma, faces a projected $2.76 per-share loss in its upcoming report, with revenue expected to drop 67.3% year-over-year.
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AAPL TSLA AMZN META AMD NVDA PEP COST ADBE GOOG AMGN HON INTC INTU NFLX ADP SBUX MRNA AAPL TSLA AMZN META AMD NVDA PEP COST ADBE GOOG AMGN HON INTC INTU NFLX ADP SBUX MRNA AAPL TSLA AMZN META AMD NVDA PEP COST ADBE GOOG AMGN HON INTC INTU NFLX ADP SBUX MRNA Stocks Esperion Therapeutics (ESPR) Misses Q4 Earnings Estimates March 10, 2026 — 07:10 am EDT Written by Zacks Equity Research for Zacks-> Esperion Therapeutics (ESPR) came out with quarterly earnings of $0.22 per share, missing the Zacks Consensus Estimate of $0.23 per share. This compares to a loss of $0.1 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an earnings surprise of -5.38%. A quarter ago, it was expected that this biopharmaceutical company would post a loss of $0.09 per share when it actually produced a loss of $0.16, delivering a surprise of -77.78%.Over the last four quarters, the company has surpassed consensus EPS estimates just once.Esperion Therapeutics, which belongs to the Zacks Medical - Drugs industry, posted revenues of $168.45 million for the quarter ended December 2025, surpassing the Zacks Consensus Estimate by 4.90%. This compares to year-ago revenues of $69.11 million. The company has topped consensus revenue estimates four times over the last four quarters.The sustainability of the stock's immediate price movement based on the recently-released numbers and future earnings expectations will mostly depend on management's commentary on the earnings call.Esperion Therapeutics shares have lost about 17.8% since the beginning of the year versus the S&P 500's decline of 0.7%.What's Next for Esperion Therapeutics?While Esperion Therapeutics has underperformed the market so far this year, the question that comes to investors' minds is: what's next for the stock?There are no easy answers to this key question, but one reliable measure that can help investors address this is the company's earnings outlook. Not only does this include current consensus earnings expectations for the coming quarter(s), but also how these expectations have changed lately.Empirical research shows a strong correlation between near-term stock movements and trends in earnings estimate revisions. Investors can track such revisions by themselves or rely on a tried-and-tested rating tool like the Zacks Rank, which has an impressive track record of harnessing the power of earnings estimate revisions.Ahead of this earnings release, the estimate revisions trend for Esperion Therapeutics was mixed. While the magnitude and direction of estimate revisions could change following the company's just-released earnings report, the current status translates into a Zacks Rank #3 (Hold) for the stock. So, the shares are expected to perform in line with the market in the near future. You can see the complete list of today's Zacks #1 Rank (Strong Buy) stocks here.It will be interesting to see how estimates for the coming quarters and the current fiscal year change in the days ahead. The current consensus EPS estimate is -$0.04 on $85.48 million in revenues for the coming quarter and $0.18 on $404.88 million in revenues for the current fiscal year.Investors should be mindful of the fact that the outlook for the industry can have a material impact on the performance of the stock as well. In terms of the Zacks Industry Rank, Medical - Drugs is currently in the top 36% of the 250 plus Zacks industries. Our research shows that the top 50% of the Zacks-ranked industries outperform the bottom 50% by a factor of more than 2 to 1.One other stock from the same industry, Nektar Therapeutics (NKTR), is yet to report results for the quarter ended December 2025. The results are expected to be released on March 12.This biopharmaceutical company is expected to post quarterly loss of $2.76 per share in its upcoming report, which represents a year-over-year change of -22.7%. The consensus EPS estimate for the quarter has been revised 7.6% higher over the last 30 days to the current level.Nektar Therapeutics' revenues are expected to be $9.54 million, down 67.3% from the year-ago quarter.

Should You Invest in Esperion Therapeutics, Inc. (ESPR)? Before you invest in Esperion Therapeutics, Inc. (ESPR), want to know the best stocks to buy for the next 30 days? Check out Zacks Investment Research for our free report on the 7 best stocks to buy.

Zacks Investment Research has been committed to providing investors with tools and independent research since 1978. For more than a quarter century, the Zacks Rank stock-rating system has more than doubled the S&P 500 with an average gain of +24.08% per year. (These returns cover a period from January 1, 1988 through May 6, 2024.)Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free reportEsperion Therapeutics, Inc. (ESPR) : Free Stock Analysis ReportNektar Therapeutics (NKTR) : Free Stock Analysis ReportThis article originally published on Zacks Investment Research (zacks.com).Zacks Investment Research The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.

Tags Stocks Zacks Zacks is the leading investment research firm focusing on stock research, analysis and recommendations. In 1978, our founder discovered the power of earnings estimate revisions to enable profitable investment decisions. Today, that discovery is still the heart of the Zacks Rank. A wealth of resources for individual investors is available at www.zacks.com. More articles by this source-> Stocks mentioned ESPR NKTR More Related Articles This data feed is not available at this time. Data is currently not available • Sign up for the TradeTalks newsletter to receive your weekly dose of trading news, trends and education. Delivered Wednesdays.

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