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NIST CAISI Issues Request for Information on Securing AI Agent Systems

Quantum Zeitgeist
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⚡ Quantum Brief
NIST’s CAISI launched a Request for Information (RFI) on securing AI agent systems, addressing unique threats like adversarial data manipulation and misaligned objectives in autonomous AI models. The RFI targets risks beyond traditional software vulnerabilities, including indirect prompt injection and data poisoning, which could compromise AI agent behavior and outputs in real-world applications. Responses, due by March 9, 2026, will shape future guidelines for measuring AI agent security, anticipating development risks, and restricting agent access in deployment environments. NIST seeks input on whether current cybersecurity frameworks suffice for AI agents, emphasizing gaps that could impact public safety and national security as adoption grows. Submissions under docket NIST-2025-0035 will inform research and best practices, focusing on proactive risk mitigation in AI agent design and deployment.
NIST CAISI Issues Request for Information on Securing AI Agent Systems

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The U.S. Department of Commerce’s National Institute of Standards and Technology (NIST) CAISI issued a Request for Information (RFI) concerning the secure development and deployment of AI agent systems. This RFI seeks insights regarding unique security challenges—including adversarial data interactions and misaligned objectives—inherent in combining AI models with software functionality. Input will inform future guidelines and best practices for AI agent security. CAISI RFI Targets AI Agent System Security Risks CAISI is requesting information to address security concerns specific to AI agent systems, which autonomously plan and act in real-world contexts. Unlike typical software, these systems face risks from adversarial data—like indirect prompt injection—and vulnerabilities stemming from insecure AI models susceptible to data poisoning. Additionally, even without malicious input, models can exhibit harmful behavior through specification gaming or misaligned goals. The request for information aims to identify how existing cybersecurity measures apply, or fall short, when protecting AI agents. CAISI specifically seeks methods for measuring agent security, anticipating risks during development, and constraining agent access within deployment environments. Responses are due by March 9, 2026, and will be used to develop future guidelines and inform ongoing research through docket number NIST-2025-0035. NIST Seeks Input on AI Agent Development & Deployment Methods The inquiry specifically targets risks beyond typical software vulnerabilities, focusing on issues like indirect prompt injection and data poisoning—methods used to manipulate model outputs. Understanding these unique threats is crucial, as broader deployment of AI agents could impact public safety and national security. The request for information also centers on quantifying agent security and proactively identifying risks during the development process. CAISI seeks input on whether current cybersecurity methods adequately address these new challenges and how to best constrain agent access within deployment environments. Responses, accepted until March 9, 2026, will shape future guidelines and research evaluating AI agent security, with submissions possible through regulations.gov under docket number NIST-2025-0035. These security challenges not only hinder adoption today but may also pose risks for public safety and national security as AI agent systems become more widely deployed. Source: https://www.nist.gov/news-events/news/2026/01/caisi-issues-request-information-about-securing-ai-agent-systems Tags: Quantum News As the Official Quantum Dog (or hound) by role is to dig out the latest nuggets of quantum goodness. There is so much happening right now in the field of technology, whether AI or the march of robots. But Quantum occupies a special space. Quite literally a special space. A Hilbert space infact, haha! Here I try to provide some of the news that might be considered breaking news in the Quantum Computing space. Latest Posts by Quantum News: Honeywell Backed Quantinuum Pursues Public Offering via SEC Filing January 14, 2026 Materials Project Cited 32,000 Times, Accelerating Battery & Quantum Computing January 14, 2026 Apache Software Foundation Unveils Apache Geode 2.0 with Java 17 Support January 14, 2026

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Source: Quantum Zeitgeist