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The Most Active Startup Acquirers Of The Past 3 Years Aren’t Always Who You’d Expect

Joanna Glasner
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⚡ Quantum Brief
Salesforce, OpenAI, and Snowflake led startup acquisitions over the past three years, with each completing six or more deals, per Crunchbase data. Salesforce’s 91 purchases in 20 years include AI-focused startups like Momentum and Cimulate AI. OpenAI, a newer acquirer, bought 16 startups in three years, targeting AI talent and tools. Recent deals include OpenClaw (acqui-hire), Astral (developer tools), and Promptfoo (AI testing), reflecting its aggressive AI expansion strategy. Snowflake made 19 acquisitions, most recently Observe, an AI observability firm with $460M in prior funding. Its focus aligns with scaling cloud and AI infrastructure amid growing demand. Big spenders differ from frequent buyers: Google’s $32B Wiz acquisition topped spending, while 2026 saw Capital One ($5.15B for Brex) and Eli Lilly ($2.4B for Orna Therapeutics) lead high-value deals. AI-driven acqui-hires and early-stage purchases remain strong, though overall startup M&A volume stays below 2021 peaks. The trend highlights talent and tech consolidation in competitive sectors.
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Joanna Glasner jglasner 0 Shares Email Facebook Twitter LinkedIn Companies that buy a lot of startups don’t always have a lot in common. Some are longstanding blue chip tech and pharmaceutical companies. Others are fast-growing venture-backed unicorns. And still others are more recent public market entrants looking to stay competitive in the age of AI. To get a sense of who’s buying in bulk, we used Crunchbase data to put together a list of 79 companies that acquired three or more seed- or venture-backed startups in the past three years. From there, we picked the most acquisitive names. The most prolific startup acquirers of the past 3 years Per Crunchbase data, the most prolific acquirers of seed- and venture-backed startups in recent years are Salesforce 1, OpenAI and Snowflake. Overall, our query showed six companies with six or more known purchases, charted below. For top-ranked Salesforce, high-volume M&A is nothing new.

The San Francisco software giant has purchased at least 91 companies in the past 20 years, per Crunchbase data. Its most recent startup purchases include Momentum, a revenue orchestration platform, and Cimulate AI, which focuses on agentic AI for e-commerce. OpenAI, by contrast, has a shorter track record of M&A shopping sprees. The pioneering generative AI company has bought 16 companies in the past three years. Among the most recent was an acqui-hire deal involving open-source AI agent OpenClaw and its creator, Peter Steinberger. This month, it also snapped up Astral, a creator of open source tools for software developers, and Promptfoo, an open-source tool for testing AI applications. Snowflake, meanwhile, has 19 acquisitions to date. Most recently, it acquired Observe, a developer of AI observability tools that previously raised more than $460 million in venture funding. Notably, recent the active acquirers list for recent years looks quite a bit different that the ranking of all-time top M&A dealmakers in the Crunchbase dataset, shown below: Highest-spending acquirers The most prolific startup buyers also aren’t always the biggest check-writers. By the latter metric, the far-and-away leader is Google, and its $32 billion acquisition of Wiz. For a broader picture view, we used Crunchbase data to put together a list of six companies that made the biggest-ticket funded startup acquisitions of the past three years. 2026 off to a promising start So far this year, it looks like the pace of startup M&A dealmaking remains fairly robust. This includes two deals in the multiple billions: Capital One’s $5.15 billion purchase of Brex and Eli Lilly’s $2.4 billion acquisition of Orna Therapeutics. The AI sector’s appetite for acqui-hires and smaller purchases of earlier-stage startups also continues to boost momentum. We’ll see if it keeps up. Related Crunchbase list: Most Prolific Funded US Startup Acquirers Of The Past 3 Years Related reading: Small And Mid-Sized Startup Purchases Are Still Well Below The 2021 Peak Crunchbase Predicts: Why The Race For Talent And Tech Could Accelerate Startup M&A In 2026 M&A The Highest On Record For Unicorn Exits In 2025 Illustration: Dom Guzman Salesforce Ventures is an investor in Crunchbase. They have no say in our editorial process. For more, head here.↩ TagsAI M&A marketing SaaS sales startups unicorn Stay up to date with recent funding rounds, acquisitions, and more with the Crunchbase Daily. You may also like Artificial intelligence • SaaS • Startups Don’t Just Talk About AI.

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