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IBM, Cleveland Clinic, and RIKEN simulate massive 12,635 atom protein with quantum computing

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⚡ Quantum Brief
A collaboration between IBM, Cleveland Clinic, and RIKEN achieved a breakthrough by simulating a 12,635-atom protein (trypsin) using a hybrid quantum-classical approach, marking a massive leap from previous sub-10-atom demonstrations. The team partitioned tasks: classical supercomputers managed structural decomposition while IBM’s ~94-qubit processors handled complex quantum chemistry calculations, later recombining results for higher accuracy. This 1,000x scaling jump—from ~10 to 12,000+ atoms—happened rapidly, suggesting accelerated progress in quantum-enabled molecular modeling for real-world applications like drug discovery. Despite the advance, classical systems still dominate workloads, with quantum processors acting as specialized accelerators rather than replacements for high-performance computing. The milestone signals quantum’s potential to tackle biologically relevant problems, though experts caution it remains an early-stage hybrid approach with significant development ahead.
IBM, Cleveland Clinic, and RIKEN simulate massive 12,635 atom protein with quantum computing

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IBM, Cleveland Clinic, and RIKEN say they simulated a 12,635-atom protein (trypsin) using a hybrid quantum + classical approach, which is way beyond the tiny toy systems we usually hear about. They split the workload so classical supercomputers handle decomposition while quantum processors (up to ~94 qubits) tackle the hard quantum chemistry pieces, then stitch it back together. The scaling jump from ~10 atoms to 12k in a short time is wild, and they claim big accuracy gains too. That said, this still feels like early-stage hybrid HPC doing most of the heavy lifting, not quantum replacing anything yet, but it does look like quantum might finally be inching toward problems that actually matter for drug discovery. submitted by /u/OkReport5065 [link] [comments]

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drug-discovery
quantum-chemistry
government-funding
quantum-computing
quantum-algorithms
quantum-hardware

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Source: Reddit r/QuantumComputing (RSS)