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Hydration Monitoring Using Urinary Biomarkers: A Hybrid Classical Quantum Predictive Modeling Framework

arXiv Quantum Physics
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⚡ Quantum Brief
Researchers from multiple institutions introduced a hybrid quantum-classical framework to predict hydration levels using urinary biomarkers like specific gravity and conductivity, leveraging data from smart toilet sensors. The study compares classical machine learning with quantum variational circuits, including a novel modular Quantum Sequential Model (QSM) designed for flexible hybrid pipelines in physiological data analysis. Experiments reveal quantum models show potential but face near-term hardware limitations, with symmetry-constrained quantum regressors offering marginal improvements over classical methods in certain cases. The work highlights opportunities for quantum machine learning in digital health, particularly in continuous monitoring systems like the Predict Health Toilet (PHT) platform. Published in April 2026, the paper underscores the need for further optimization as quantum hardware matures, while demonstrating early viability for real-world health applications.
Hydration Monitoring Using Urinary Biomarkers: A Hybrid Classical Quantum Predictive Modeling Framework

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Quantum Physics arXiv:2604.15381 (quant-ph) [Submitted on 16 Apr 2026] Title:Hydration Monitoring Using Urinary Biomarkers: A Hybrid Classical Quantum Predictive Modeling Framework Authors:Saul Gonzalez-Bermejo, Tommaso Albrigi, Borja Vazquez-Morado, Urko Regueiro-Ramos, Daniel Casado-Fauli, Sergi Consul-Pacareu, Laia Alentorn, Jordi Ferre, Valentino Asole, Parfait Atchade-Adelomou View a PDF of the paper titled Hydration Monitoring Using Urinary Biomarkers: A Hybrid Classical Quantum Predictive Modeling Framework, by Saul Gonzalez-Bermejo and 8 other authors View PDF HTML (experimental) Abstract:Hydration status is a key physiological indicator associated with cellular homeostasis, renal function, and overall health. Recent advances in smart sensing environments enable passive monitoring of urinary biomarkers that can provide continuous insight into hydration dynamics. In this work, we investigate predictive modeling approaches for hydration monitoring using biomarker data collected through the Predict Health Toilet (PHT) system. The problem is formulated as a regression task using urinary indicators such as urine specific gravity, conductivity, and volume. We evaluate classical machine learning models and quantum machine learning architectures based on variational quantum circuits. In particular, we introduce a modular Quantum Sequential Model (QSM) designed to construct flexible hybrid quantum classical predictive pipelines. Experimental results compare classical regression models, symmetry-constrained quantum regressors, and QSM architectures. The results provide insights into the potential role of quantum machine learning in digital health monitoring systems and highlight the opportunities and current limitations of near-term quantum computing for physiological data analysis. Comments: Subjects: Quantum Physics (quant-ph) Cite as: arXiv:2604.15381 [quant-ph] (or arXiv:2604.15381v1 [quant-ph] for this version) https://doi.org/10.48550/arXiv.2604.15381 Focus to learn more arXiv-issued DOI via DataCite (pending registration) Submission history From: Parfait Atchade [view email] [v1] Thu, 16 Apr 2026 01:13:13 UTC (215 KB) Full-text links: Access Paper: View a PDF of the paper titled Hydration Monitoring Using Urinary Biomarkers: A Hybrid Classical Quantum Predictive Modeling Framework, by Saul Gonzalez-Bermejo and 8 other authorsView PDFHTML (experimental)TeX Source view license Current browse context: quant-ph new | recent | 2026-04 References & Citations INSPIRE HEP NASA ADSGoogle Scholar Semantic Scholar export BibTeX citation Loading... BibTeX formatted citation × loading... Data provided by: Bookmark Bibliographic Tools Bibliographic and Citation Tools Bibliographic Explorer Toggle Bibliographic Explorer (What is the Explorer?) Connected Papers Toggle Connected Papers (What is Connected Papers?) Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart Citations?) Code, Data, Media Code, Data and Media Associated with this Article alphaXiv Toggle alphaXiv (What is alphaXiv?) Links to Code Toggle CatalyzeX Code Finder for Papers (What is CatalyzeX?) DagsHub Toggle DagsHub (What is DagsHub?) GotitPub Toggle Gotit.pub (What is GotitPub?) Huggingface Toggle Hugging Face (What is Huggingface?) ScienceCast Toggle ScienceCast (What is ScienceCast?) Demos Demos Replicate Toggle Replicate (What is Replicate?) Spaces Toggle Hugging Face Spaces (What is Spaces?) Spaces Toggle TXYZ.AI (What is TXYZ.AI?) Related Papers Recommenders and Search Tools Link to Influence Flower Influence Flower (What are Influence Flowers?) Core recommender toggle CORE Recommender (What is CORE?) Author Venue Institution Topic About arXivLabs arXivLabs: experimental projects with community collaborators arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs. Which authors of this paper are endorsers? | Disable MathJax (What is MathJax?)

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Source: arXiv Quantum Physics